TECNOPOLO DI MODENA - Parco Scientifico Tecnologico di Mirandola, via 29 Maggio 6 - Mirandola (MO)
Il laboratorio di ricerca Tecnopolo TPM “Mario Veronesi” di Mirandola mette a disposizione delle imprese principalmente del comparto biomedicale, ma anche cosmetologico e agro-alimentare, servizi di alto livello per la ricerca applicata, lo sviluppo industriale e la convalida di prodotti, oltre che consulenze per la formazione continua di tecnici e ricercatori.
È porta di accesso privilegiata alla Rete Alta Tecnologia, è certificato in accordo alle UNI EN ISO 13485 e 9001, opera in connessione con la Sanità provinciale e regionale e in collegamento con network nazionali ed internazionali. È organizzato su un modello integrato fatto di ricerca, servizi avanzati, formazione e incubazione presso il TPM Cube.
Il TPM è in grado di risolvere problematiche altamente complesse tramite analisi biologiche e di biocompatibilità, analisi di performance, test specifici e su misura del richiedente adottando protocolli che tutelano la riservatezza e la proprietà intellettuale dei progetti o ricerche affidati.
In collaborazione con l’Università di MO e RE, gestisce i laboratori:
· TOP, Tossicologia e Proteomica
· MAB, Microscopia applicata e Biologia Cellulare
· MS2, Materiali, Sensori e Sistemi
· PoS, Analisi chimico/fisiche
· Usability
Grazie alle competenze specifiche del team e all’utilizzo delle più recenti e avanzate tecnologie, è un luogo dove imprese e competenze scientifiche si incontrano per creare, risolvere ed accelerare opportunità produttive personalizzate per il richiedente.
Tossicologia e Proteomica
Microscopia applicata e Biologia Cellulare
Materiali, Sensori e Sistemi
Analisi chimico/fisiche
Aziende del settore Life Science
Aziende del settore manifatturiero
Startup del settore Life Science
Centri di ricerca del settore Life Science
Enti nazionali ed europei
Design and development of new products / processes
- Conceptual design: analysis of customer needs and development of alternative concepts - Alberto Ferrari
- Detail design: Design archetypes , parametric models (CAD) - Alberto Ferrari
- Detail design:static, dynamic, elastodynamic structural, thermo structural and crash analysis (FEM) - Alberto Ferrari
- Detail design: internal and external three-dimensional thermo - fluid dynamics of components, machines and systems (CFD) - Alberto Ferrari
- Detail design: lumped parameter and one-dimensional fluid dynamic analysis of circuits, components, machines and systems - Alberto Ferrari
- Design for Ergonomics (Digital Mock Up, HMI - Human Machine Interface, User centered design, User experience, Usability) - Alberto Ferrari
- Design for Manufacturability / Analysis of technological processes for polymers (CAE): plastic deformation, injection molding, extrusion, thermoforming - Alberto Ferrari
- Rapid prototyping & Additive manufacturing - Alberto Ferrari
- Testing and prototyping: Structural analysis (strain gauge, fatigue) - Alberto Ferrari
- Testing and measuring: dimensional and geometric control; Reverse Engineering - Alberto Ferrari
Manufactur processes
- Processes of production / machining of products in polymer materials - Alberto Ferrari
- Microprocessing (micro-milling, -drilling, -laser, -waterjet, etc.) - Alberto Ferrari
- Additive manufacturing processes (3D printing, SLA rapid prototyping, etc.) - Alberto Ferrari
- Surface treatments of chemical and physical functionalization of materials (texturing, SOL-GEL, plasma activation, etc.) - Alberto Ferrari
Maintenance and diagnostics
- Sensors for predictive maintenance - Alberto Ferrari
- Thermography - Alberto Ferrari
Materials
- Thermoplastic polymeric materials - Simone Roncioni
- Polymer matrix composites and nanocomposites - Aurora Cuoghi
- Polymeric nanofibers - Aurora Cuoghi
- Micro-nano materials functionalized - Aurora Cuoghi
Modeling of physical systems and simulation
- Discrete events mathematical modeling of systems and processes - Alberto Ferrari
- Non-parametric modeling (neural networks, etc.) - Alberto Ferrari
- Acquisition and pre-processing of signals for model identification - Alberto Ferrari
Automation: actuators and robotics
- Micro-actuators based on MEMS - Alberto Ferrari
- Hardware design - Alberto Ferrari
- Designe of specific software application (acquisition, processing, control, supervision, ...) - Alberto Ferrari
Sensors
- Mechanical sensors (accelerometers, gyroscopes, strain gauges, microphones); Tactile , force, torque sensors. Doppler laser sensors - Alberto Ferrari
- Optical sensors, waveguides and photonic structures, optics fibers - Alberto Ferrari
- Satellite sensors (GPS, GLONASS, Galileo ....) - Alberto Ferrari
- Detectors of ionizing radiation (X-rays, gamma, radon) - Alberto Ferrari
- Biosensors (enzymes, cells, antibodies,analyte and ions) - Alberto Ferrari
- Sensors for flow, flow rate and pressure of liquids and gases, and for microfluidics - Alberto Ferrari
- Electrical, power and magnetic sensors - Alberto Ferrari
- Chemical, gas, indoor air quality sensors, Lab-on-Chip - Alberto Ferrari
- Integrated electronics of control and front-end, with analysis of the accuracy of the acquisition chain - Alberto Ferrari
- Signal interface integration, wireless systems and wireless sensor networks - Alberto Ferrari
- Software for measuring instruments and measurements - Alberto Ferrari
- State of the art, norms analysis, standards and background art analysis of sensors - Alberto Ferrari
Biosensors
- Design, production and validation of chemo- and opto- electronic biosensors for nucleic acids detection - Alberto Ferrari
- Design, production and validation of bio-funcionalized surfaces for biosensing application - Alberto Ferrari
- "Transient and stable" cellular bio-sensors design, construction and validation - Elena Veronesi
- Design, production and validation of molecular biosensors (based on bistable plasmid) for RNA and peptides fluorescence detection - Elena Veronesi
- Recombinant vectors design and realization for cellular biosensors production - Elena Veronesi
- Nanoparticles and surfaces microscopy characterization and bio-chemical derivatization - Aurora Cuoghi
- Plasmid production - Elena Veronesi
- Microscopy and nano -scopy, nanomechanics characterization in vitro with AFM technology - Elena Veronesi
- 2D, 3D and 4D imaging and quantification - Elena Veronesi
Devices and prostheses
- Assessment of the requirements by clinical experts - Alberto Ferrari
- Numerical design of devices - Alberto Ferrari
- Preclinical evaluation of devices by numerical simulations - Alberto Ferrari
- Microscopic/nanoscopic/nanomechanical, mechanical and in vitro functional characterization of the device - Simone Roncioni
- In vivo functional characterization of the device - Elena Veronesi
- Topographic and microarchitectural characterization of the biomaterial/device - Elena Veronesi
- Analysis by means of molecular biology as well as biochemical, immunoenzymatic, histologic, immunohistochemical, biomechanical, radiographic - Elena Veronesi
- Evaluation of the bio-safety of medical devices in vitro - Aurora Cuoghi
Drug delivery
- In vitro drug release of nanoparticles and complex scaffolds - Elena Veronesi
- In vitro evaluation of the cell response to drug delivery systems - Elena Veronesi
Drug discovery
- Evaluation of the chemical stability - Aurora Cuoghi
- Evaluation of the stability of a molecule in the plasma - Aurora Cuoghi
- Drug study on human endothelial cells - Elena Veronesi
- Drug study on human and animal perycites - Elena Veronesi
- Drug study on human and animal fibroblasts - Elena Veronesi
- Physico-chemical characterisation of new compounds - Aurora Cuoghi
- Study on drug resitance/drug susceptibility on cell models and circulating tumor cell - Elena Veronesi
e-Care
- Solution development on computer aided medicine - Alberto Ferrari
- Data fusion e data processing - Alberto Ferrari
- Data mining - Alberto Ferrari
- Telemedicine - Alberto Ferrari
- Development of e-care prototype solutions - Alberto Ferrari
- Integration of e-care prototype solutions - Alberto Ferrari
- Testing and benchmarking of e-care prototype solutions - Alberto Ferrari
Omics
- Preprocessing and sample storage (biobanking) - Aurora Cuoghi
- Meta-analysis - Aurora Cuoghi
- Sample processing - Aurora Cuoghi
- Quality assessment - Aurora Cuoghi
- Data processing - Aurora Cuoghi
- Proteomics - Aurora Cuoghi
- Identification and validation of biomarkers - Aurora Cuoghi
Personal Health System
- Analysis of (clinical) functional requirements - Alberto Ferrari
- Selection and interfacing of sensors and actuators - Alberto Ferrari
- Selection of the communication layer a/o mobile platform - Alberto Ferrari
- HW/SW design for resources optimization - Alberto Ferrari
- Users interface design - Alberto Ferrari
- Musculoskeletal modelling - Alberto Ferrari
- Neurocognitive modelling - Alberto Ferrari
- Clinical assessment - Aurora Cuoghi
Preclinical studies
- Test of proliferation, migration, differentiation, adhesion, viability, cell apoptosis - Elena Veronesi
- Histological and immunohistochemical evaluations - Elena Veronesi
- Histological and immunohistochemical evaluations (quantitative computed) - Elena Veronesi
- Microtomography evaluation 3D and 4D in vitro, ex vivo - Elena Veronesi
- Radiographic assessment (Rx) - Elena Veronesi
- Biomechanical evaluations - Alberto Ferrari
- Dynamic histomorphometry - Elena Veronesi
- Ultrastructural microscopy - Elena Veronesi
Scaffold
- Design and development of scaffolds for soft tissue regeneration - Aurora Cuoghi
- Design and development of scaffolds for regeneration of hard tissues and ligaments - Aurora Cuoghi
- Design and development of scaffolds for organ regeneration - Aurora Cuoghi
- Design of protocols for pre-clinical evaluation (in vitro and in vivo) - Elena Veronesi
- Design of protocols for clinical evaluation - Aurora Cuoghi
- Design and development of nanofibrous scaffolds mimicking the extracellular matrix - Aurora Cuoghi
- Deposition of thin films and coatings - Aurora Cuoghi
- Development of sinterable polymeric particles - Aurora Cuoghi
- Scaffold functionalization with proteins, drugs and cells - Elena Veronesi
- In vitro mechanical characterization of scaffolds - Elena Veronesi
- Chemico-physical-morphological-ultrastructural and thermo-mechanical characterization of the scaffolds - Aurora Cuoghi
- Assessment of the chemical stability and maintenance of the physico-mechanical properties of the scaffolds - Alberto Ferrari
- Biologic evaluation of scaffoldswith 3D cultures in dynamic regime in bioreactor - Elena Veronesi
Therapeutic and diagnostic biomedical equipment
- Comparative numerical analysis - Alberto Ferrari
- Numerical optimization of biomedical instrumentation - Alberto Ferrari
- Therapeutic biomedical equipments: selection and interconnection of sensors and actuators - Alberto Ferrari
- Therapeutic biomedical equipments: design of the storage and transmission systems - Alberto Ferrari
- Therapeutic biomedical equipments: geometric measurements on 3D and 4D images - Alberto Ferrari
- Diagnostic biomedical equipments: 2D and 3D alignment of Radiological Data - Alberto Ferrari
Advanced Therapies
- Advanced Therapy Design (fat cells) - Elena Veronesi
- Advanced Therapy Design (skeletal muscle cells) - Elena Veronesi
- Isolation, target carachterisation (fat cells) - Elena Veronesi
- Scaffold or substrate identification (skeletal muscle cells) - Elena Veronesi
- Isolation, target carachterisation (skeletal muscle cells) - Elena Veronesi
- Extensive cellular manipulation - Elena Veronesi
- In vitro and in vivo pre-clinical validation (fat cells) - Elena Veronesi
- In vitro and in vivo pre-clinical validation (epithelial cells) - Elena Veronesi
- In vitro and in vivo pre-clinical validation (skeletal muscle cells) - Elena Veronesi